A major European biopharmaceutical company was struggling to achieve the required purity and experiencing extremely high energy consumption due to the limited separation efficiency of traditional equipment when extracting high-value plants. Cohen's soluti
Before introducing Cohen Machinery's intelligent system, the production base had long relied on traditional centrifugal separation equipment. However, with continuous upgrades in bioprocesses and increased fermentation broth droplets, the outdated equipment could no longer meet modern production demands. Due to the uneven separation efficiency of the existing equipment, fine splashes in the fermentation broth could not be completely removed, resulting in a large amount of residual solids flowing directly into the downstream fine filtration stage, causing severe filter clogging.
Currently, the production team is frequently forced to use the equipment to clean and replace filter media, which not only exacerbates the severe consumption of high-value biological materials during operation but also significantly increases the cost per batch. Furthermore, the lack of real-time data acquisition and equipment status monitoring hinders maintenance work.
This client's biopharmaceutical production line requires continuous 24-hour operation; a single unit failure could mean the loss of bioactive substances worth hundreds of thousands of euros. The client's existing separation equipment suffered from poor se
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Centrifugation Technology Breaks Through the Limits of Plant Extract Purity: A major European biopharmaceutical company was struggling to achieve the required purity and consume excessive energy when extracting high-value plants due to the limited separat
Fully sealed design: prevents materials from coming into contact with the atmosphere, fully complying with GMP standards and aseptic production requirements.
Intelligent status monitoring: Equipped with highly sensitive vibration and temperature sensors, it can issue early warning notifications 72 hours before a fault occurs.
Material upgrade: All parts in contact with materials are made of high-grade SS316L stainless steel and undergo extreme mirror polishing.
Upgrade Results: Extraction purity increased from the traditional 85% to over 99.5%, while preserving the biological activity of the extracts, perfectly aligning with international pharmaceutical purity standards.
Cohen Solutions not only solved our separation purity problem, but its early warning system also gave us confidence in our production operations. This was a very successful technology upgrade.
It significantly reduces the pressure on subsequent filtration and extends the service life of the filter element by 3 times.
This successfully prevented the bioactive batches from becoming invalid due to sudden downtime.
The intelligent early warning system allows the team to utilize planned downtime for rapid maintenance.
The optimized frequency converter control system significantly reduces peak operating energy consumption.